Synthesis of new oxindole derivatives containing benzothiazole and thiazolidinone moieties using nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU) as catalyst

Authors

ROBABEH BAHARFAR
NARGES SHARIATI

DOI

10.3906/kim-1408-26

Abstract

A facile one-pot synthesis of novel oxindole derivatives bearing benzothiazolylmethyl-2-thioxothiazolidin-4-one was accomplished via one-pot reaction of 5-oxoindolinylidene rhodanine-3-acetic acid derivatives, 2-aminothiophenol, and triphenyl phosphite in the presence of tetrabutylammonium bromide (TBAB) and nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU) as heterogeneous reusable nanocatalyst. The target compounds were obtained in excellent yields (85%--92%) and short reaction times under fairly mild reaction conditions.

Keywords

Oxindole derivatives, benzothiazoles, 4-thiazolidinones, nano silica-bonded 5-n-propyl-octahydro-pyrimido [1, 2-a]azepinium chloride, nano silica-supported catalyst

First Page

235

Last Page

243

Recommended Citation

BAHARFAR, ROBABEH and SHARIATI, NARGES (2015) "Synthesis of new oxindole derivatives containing benzothiazole and thiazolidinone moieties using nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU) as catalyst," Turkish Journal of Chemistry: Vol. 39: No. 2, Article 3. https://doi.org/10.3906/kim-1408-26
Available at: https://journals.tubitak.gov.tr/chem/vol39/iss2/3