Turkish Journal of Chemistry
Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor
A new, less expensive, solvent-free procedure was developed for the synthesis of some new derivatives of various fused heterocyclic ring systems, namely azolopyridazine, azolotriazine, azinotriazine, thienopyridine, and pyrazolopyridine. The structures of the products prepared were established by their spectral data and elemental analyses. Eight compounds were evaluated for their in vitro antimicrobial activity. Some of the tested compounds exhibited moderate to significant antibacterial and antifungal activities.
Azolopyridazine, azolotriazine, azinotriazine, thienopyridine, pyrazolopyridine, antimicrobial activities
GOMHA, SOBHI MOHAMED; SHAWALI, AHMAD SAMI; and ABDELHAMID, ABDOU OSMAN
"Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor,"
Turkish Journal of Chemistry: Vol. 38:
5, Article 18.
Available at: https://journals.tubitak.gov.tr/chem/vol38/iss5/18