Turkish Journal of Chemistry
Abstract
The Heck coupling of haloarenes with various alkenes was successfully performed in the presence of 0.25 mol % PdCl_2 and 0.5 mol % biphenyl-4-yl-[4(5)-(biphenyl-4-yl)-1H-imidazol-2-yl]ketone 2f as a ligand with Na_2CO_3 as optimal base, in a 1:1 mixture of H_2O/DMF as the reaction solvent at 80 ^°C for 8 h. Imidazole 2f was found to be an inexpensive, air-stable, easily available, and efficient ligand in the palladium-catalyzed Heck reactions of aryl iodides (76 %--94 %), bromides (52 %--79 %), and chlorides (40 %--70 %).
DOI
10.3906/kim-1307-18
Keywords
Aroylimidazoles, PdCl_2, Heck reaction, aqueous medium
First Page
547
Last Page
552
Recommended Citation
AMINI, M, AMINI, S. M, EFTEKHARI-SIS, B, & KEIVANLOO, A (2014). Application of 3-aroyl-4(5)-arylimidazols as efficient ligands in Pd-catalyzed Heck reactions. Turkish Journal of Chemistry 38 (4): 547-552. https://doi.org/10.3906/kim-1307-18
