Synthesis, spectral characterisation, electrochemical, and fluorescence studies of biologically active novel Schiff base complexes derived from E-4-(2-hydroxy-3-methoxybenzlideneamino)-N-(pyrimidin-2-yl)benzenesulfonamide

Authors

VALARMATHY GOVINDARAJ
SUBBALAKSHMI RAMANATHAN

DOI

10.3906/kim-1301-83

Abstract

A new Schiff base was prepared from 2-sulphanilamidopyrimidine and 2-hydroxy-3-methoxybenzaldehyde in ethanolic media and it was complexed with Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) ions. The synthesised ligand and complexes were characterised by IR, UV, ^1H and ^{13}C NMR, elemental analysis, cyclic voltammetry, EPR, molar conductance, and magnetic susceptibility. The reasonable shifts in FT-IR and NMR spectral signals of the complexes with respect to the free ligand confirm good coordination of the Schiff-base ligand with the metal through imine nitrogen and oxygen atoms of Schiff base moiety. The Schiff-base ligand and the complexes were screened for antimicrobial activity and fluorescent behaviour. From the analytical and spectral data, the stoichiometry was found to be 1:2 for all the complexes. An octahedral structure was proposed. All the complexes were found to be active against bacteria and fungi.

Keywords

Schiff base, 2-sulphanilamidopyrimidine, 2-hydroxy-3-methoxybenzaldehyde, metal complexes, biological activity, fluorescent behaviour

First Page

521

Last Page

530

Recommended Citation

GOVINDARAJ, VALARMATHY and RAMANATHAN, SUBBALAKSHMI (2014) "Synthesis, spectral characterisation, electrochemical, and fluorescence studies of biologically active novel Schiff base complexes derived from E-4-(2-hydroxy-3-methoxybenzlideneamino)-N-(pyrimidin-2-yl)benzenesulfonamide," Turkish Journal of Chemistry: Vol. 38: No. 4, Article 1. https://doi.org/10.3906/kim-1301-83
Available at: https://journals.tubitak.gov.tr/chem/vol38/iss4/1