Turkish Journal of Chemistry
DOI
10.3906/kim-1308-27
Abstract
A facile synthesis of a series of new 5-bromotropono[c]pyrazole derivatives (3 and 10--15) as well as 5-bromotropono[c]isoxazole (17) is described, involving a condensation reaction of 3-acetyl-5-bromotropolone (1) with hydrazine monohydrate (2), arylhydrazine hydrochlorides (4--9), and hydroxylamine hydrochloride (16), respectively. All the synthesized compounds were obtained in good yields of 56%--77% and their structures were characterized by spectral data and HRMS.
Keywords
Tropono[c]pyrazole, tropono[c]isoxazole, condensation reaction, hydrazine monohydrate, arylhydrazine, hydroxylamine
First Page
470
Last Page
476
Recommended Citation
LI, YANG; XU, LIANGYU; and GAO, WENTAO
(2014)
"Facile synthesis of 5-bromotropono[c]-fused pyrazoles and isoxazole,"
Turkish Journal of Chemistry: Vol. 38:
No.
3, Article 12.
https://doi.org/10.3906/kim-1308-27
Available at:
https://journals.tubitak.gov.tr/chem/vol38/iss3/12
