Turkish Journal of Chemistry
Abstract
Four 6-aminopenicillanic acid moieties were grafted at either rim of calix[4]arene, giving 2 novel generations of penicillin, which were named calixpenam. Antibiotic tests showed that they have amplified activity with respect to the corresponding penams against 3 gram-positive nonpenicillinase-producing strains of Streptococcus.
DOI
10.3906/kim-1307-32
Keywords
Calixpenam, Calixarene, 6-aminopenicillanic acid, nonpenicillinase, Streptococcus strains
First Page
288
Last Page
296
Recommended Citation
PUR, F. N, & DILMAGHANI, K. A (2014). Calixpenams: synthesis, characterization, and biological evaluation of penicillins V and X clustered by calixarene scaffold. Turkish Journal of Chemistry 38 (2): 288-296. https://doi.org/10.3906/kim-1307-32
