Turkish Journal of Chemistry
Article Title
DOI
10.3906/kim-1304-72
Abstract
2-Methoxyethyl, 2-diethylaminoethyl, and 2-phenylethyl-substituted N-heterocyclic carbene (NHC) precursors were treated with Ag_2CO_3 to yield silver(I)-NHC complexes (1a--g) in dichloromethane as a solvent at room temperature. The 7 new silver-NHC complexes were fully characterized by means of ^1H NMR, ^{13}C NMR, and elemental analysis techniques. Using the agar dilution procedure recommended by the Laboratory and Clinical Standards Institute, the antimicrobial activities of all the silver-NHC complexes were studied against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).
Keywords
N-Heterocyclic carbene, benzimidazol-2-ylidene, silver complex, antimicrobial activity, medical inorganic chemistry
First Page
1007
Last Page
1013
Recommended Citation
GÖK, YETKİN; AKKOÇ, SENEM; ÇELİKAL, ÖZLEM ÖZEROĞLU; ÖZDEMİR, İLKNUR; GÜNAL, SELAMİ; and SAYIN, ELİF
(2013)
"N-functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies,"
Turkish Journal of Chemistry: Vol. 37:
No.
6, Article 16.
https://doi.org/10.3906/kim-1304-72
Available at:
https://journals.tubitak.gov.tr/chem/vol37/iss6/16
