Turkish Journal of Chemistry
Abstract
2-Methoxyethyl, 2-diethylaminoethyl, and 2-phenylethyl-substituted N-heterocyclic carbene (NHC) precursors were treated with Ag_2CO_3 to yield silver(I)-NHC complexes (1a--g) in dichloromethane as a solvent at room temperature. The 7 new silver-NHC complexes were fully characterized by means of ^1H NMR, ^{13}C NMR, and elemental analysis techniques. Using the agar dilution procedure recommended by the Laboratory and Clinical Standards Institute, the antimicrobial activities of all the silver-NHC complexes were studied against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).
DOI
10.3906/kim-1304-72
Keywords
N-Heterocyclic carbene, benzimidazol-2-ylidene, silver complex, antimicrobial activity, medical inorganic chemistry
First Page
1007
Last Page
1013
Recommended Citation
GÖK, Y, AKKOÇ, S, ÇELİKAL, Ö. Ö, ÖZDEMİR, İ, GÜNAL, S, & SAYIN, E (2013). N-functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies. Turkish Journal of Chemistry 37 (6): 1007-1013. https://doi.org/10.3906/kim-1304-72
