Turkish Journal of Chemistry
Synthesis of 3,4-diaryl-1-phenyl-4,5-dihydro-1H-pyrazole-5-carbonitriles via 1,3-dipolar cycloaddition reactions
Nitrile imines generated by the oxidative dehydrogenation of aromatic aldehyde phenylhydrazones with chloramine-T as a catalytic dehydrogenating agent were trapped in situ by 4-methoxy cinnamonitrile to afford 3,4-diaryl-1-phenyl-4,5-dihydro-1H-pyrazole-5-carbonitrile in moderate to good yields. The structures of the cycloadducts were confirmed by spectral studies and elemental analysis.
Pyrazoles, nitrile imines, chloramine-T, dipolar, cycloaddition
PRABHASHANKAR, JAYAROOPA; GOVINDAPPA, VASANTH KUMAR; and KARIYAPPA, AJAY KUMAR
"Synthesis of 3,4-diaryl-1-phenyl-4,5-dihydro-1H-pyrazole-5-carbonitriles via 1,3-dipolar cycloaddition reactions,"
Turkish Journal of Chemistry: Vol. 37:
5, Article 16.
Available at: https://journals.tubitak.gov.tr/chem/vol37/iss5/16