Synthesis of 3,4-diaryl-1-phenyl-4,5-dihydro-1H-pyrazole-5-carbonitriles via 1,3-dipolar cycloaddition reactions

Authors

JAYAROOPA PRABHASHANKAR
VASANTH KUMAR GOVINDAPPA
AJAY KUMAR KARIYAPPA

Abstract

Nitrile imines generated by the oxidative dehydrogenation of aromatic aldehyde phenylhydrazones with chloramine-T as a catalytic dehydrogenating agent were trapped in situ by 4-methoxy cinnamonitrile to afford 3,4-diaryl-1-phenyl-4,5-dihydro-1H-pyrazole-5-carbonitrile in moderate to good yields. The structures of the cycloadducts were confirmed by spectral studies and elemental analysis.

DOI

10.3906/kim-1209-52

Keywords

Pyrazoles, nitrile imines, chloramine-T, dipolar, cycloaddition

First Page

853

Last Page

857

Recommended Citation

PRABHASHANKAR, JAYAROOPA; GOVINDAPPA, VASANTH KUMAR; and KARIYAPPA, AJAY KUMAR (2013) "Synthesis of 3,4-diaryl-1-phenyl-4,5-dihydro-1H-pyrazole-5-carbonitriles via 1,3-dipolar cycloaddition reactions," Turkish Journal of Chemistry: Vol. 37: No. 5, Article 16. https://doi.org/10.3906/kim-1209-52
Available at: https://journals.tubitak.gov.tr/chem/vol37/iss5/16