Synthesis, characterization, and antimicrobial activity of some new phosphorus macrocyclic compounds containing pyrazole rings

Authors

Tarik El-Sayed ALI
Salah Abdel-Aziz ABDEL-GHAFFAR
Kamilia Mohamed EL-MAHDY
Somaia Mohamed ABDEL-KARIM

Abstract

A simple synthetic method is reported for the preparation of some new phosphorus macrocycles in which the pyrazole rings are appended to a phosphorus atom. The methodology is based on the cyclocondensation reaction of bis(4-formylpyrazolyl) phosphine oxide(1a, 1b) with nitrogen nucleophiles that contain active terminal amino groups. The antimicrobial activities of the synthesized compounds were assayed.

DOI

10.3906/kim-1205-18

Keywords

Phosphorus macrocycles, pyrazole, cyclocondensation, nitrogen nucleophiles

First Page

160

Last Page

169

Recommended Citation

ALI, T. E, ABDEL-GHAFFAR, S. A, EL-MAHDY, K. M, & ABDEL-KARIM, S. M (2013). Synthesis, characterization, and antimicrobial activity of some new phosphorus macrocyclic compounds containing pyrazole rings. Turkish Journal of Chemistry 37 (1): 160-169. https://doi.org/10.3906/kim-1205-18