Synthesis, characterization, and antimicrobial activity of some new phosphorus macrocyclic compounds containing pyrazole rings

Authors

Tarik El-Sayed ALI
Salah Abdel-Aziz ABDEL-GHAFFAR
Kamilia Mohamed EL-MAHDY
Somaia Mohamed ABDEL-KARIM

DOI

10.3906/kim-1205-18

Abstract

A simple synthetic method is reported for the preparation of some new phosphorus macrocycles in which the pyrazole rings are appended to a phosphorus atom. The methodology is based on the cyclocondensation reaction of bis(4-formylpyrazolyl) phosphine oxide(1a, 1b) with nitrogen nucleophiles that contain active terminal amino groups. The antimicrobial activities of the synthesized compounds were assayed.

Keywords

Phosphorus macrocycles, pyrazole, cyclocondensation, nitrogen nucleophiles

First Page

160

Last Page

169

Recommended Citation

ALI, Tarik El-Sayed; ABDEL-GHAFFAR, Salah Abdel-Aziz; EL-MAHDY, Kamilia Mohamed; and ABDEL-KARIM, Somaia Mohamed (2013) "Synthesis, characterization, and antimicrobial activity of some new phosphorus macrocyclic compounds containing pyrazole rings," Turkish Journal of Chemistry: Vol. 37: No. 1, Article 12. https://doi.org/10.3906/kim-1205-18
Available at: https://journals.tubitak.gov.tr/chem/vol37/iss1/12