Simultaneous determination of dopamine, uric acid, and tryptophan using an MWCNT modified carbon paste electrode by square wave voltammetry

Authors

HADI BEITOLLAHI
ALIREZA MOHADESI
SAEEDEH KHALILIZADEH MAHANI
HASSAN KARIMI MALEH
ALI AKBARI

DOI

10.3906/kim-1112-5

Abstract

A highly sensitive method was investigated for the simultaneous determination of dopamine (DA), uric acid (UA), and tryptophan (TRP) using a multiwall carbon nanotubes/5-amino-3',4'-dimethoxy-biphenyl-2-ol modified carbon paste electrode (5ADMBCNPE). The 5ADMBCNPE displayed excellent electrochemical catalytic activities towards the oxidation of DA, UA, and TRP. The electrochemical profile of the proposed modified electrode was analyzed by cyclic voltammetry (CV), which showed a shift in the oxidation peak potential of DA at 160 mV to a less positive value compared with an unmodified carbon paste electrode. Square wave voltammetry (SWV) in 0.1 M phosphate buffer solution (PBS) at pH 7.0 was performed to determine DA in the range from 1.2 to 800.0 \mu M, with a detection limit of 0.16 \mu M. The present method was applied to the determination of DA in some real samples.

Keywords

Dopamine, uric acid, tryptophan, carbon nanotube paste electrode, modified electrode

First Page

526

Last Page

536

Recommended Citation

BEITOLLAHI, HADI; MOHADESI, ALIREZA; MAHANI, SAEEDEH KHALILIZADEH; MALEH, HASSAN KARIMI; and AKBARI, ALI (2012) "Simultaneous determination of dopamine, uric acid, and tryptophan using an MWCNT modified carbon paste electrode by square wave voltammetry," Turkish Journal of Chemistry: Vol. 36: No. 4, Article 4. https://doi.org/10.3906/kim-1112-5
Available at: https://journals.tubitak.gov.tr/chem/vol36/iss4/4