Turkish Journal of Chemistry
DOI
10.3906/kim-1111-1
Abstract
Reaction of an isocyanide with an iminium ion intermediate, formed by reaction between 2-oxo-2-phenylacetaldehyde and a secondary amine in the presence of silica nanoparticles, proceeds smoothly at room temperature to afford ketoamide derivatives in high yields.
Keywords
Silica nanoparticles, multicomponent reaction, isocyanide, 2-oxo-2-phenylacetaldehyde, secondary amine, iminium ion
First Page
467
Last Page
476
Recommended Citation
RAMAZANI, ALI; DASTANRA, KOUROSH; NASRABADI, FATEMEH ZEINALI; KARIMI, ZAHRA; ROUHANI, MORTEZA; and HOSSEINI, MEHDI
(2012)
"Silica nanoparticles as a high efficient catalyst for the one-pot synthesis of 3-oxo-3-phenylpropanamid derivatives from isocyanides, phenylacetaldehyde and secondary amines,"
Turkish Journal of Chemistry: Vol. 36:
No.
3, Article 10.
https://doi.org/10.3906/kim-1111-1
Available at:
https://journals.tubitak.gov.tr/chem/vol36/iss3/10
