Turkish Journal of Chemistry
Abstract
Two new triterpene glycosides, 3-O-\beta-D-glucopyranosyl- (1\to 4)-\beta-D-xylopyranosyl-(1\to 3)-\alpha-L-rhamnopyranosyl- (1\to 3)-\alpha-L-arabinopyranosyl olean-12-ene 28-O-\beta -D- glucopyranosyl-(1\to 6)-\beta-D-glucopyranosyl ester (gazipashoside A, 1) and 3-O-\beta-D-glucopyranosyl-(1\to 4)-\beta-D-xylopyranosyl- (1\to 3)-\alpha-L-rhamnopyranosyl-(1\to 2)-\alpha-L-arabinopyranosyl hederagenin 28-O-\beta -D-glucopyranosyl-(1\to 6)-\beta-D-glucopyranosyl ester (gazipashoside B, 2), were isolated together with 11 known compounds including 7 triterpene, 1 flavonoid, and 3 iridoidal metabolites from the aerial parts of Cephalaria gazipashensis (Dipsacaceae). The structures of all compounds were elucidated by extensive evaluation of the spectroscopic data (1D- and 2D- NMR, HRESI-MS), as well as chemical examinations. The antimicrobial effects of all pure compounds were tested against gram-positive and gram-negative bacteria. The results indicated that the 2 new triterpene glycosides might be acceptable as antimicrobial active agents.
DOI
10.3906/kim-1105-32
Keywords
Gazipashoside A, gazipashoside B, Dipsacaceae, Cephalaria gazipashensis, triterpene glycoside, antimicrobial activity
First Page
323
Last Page
334
Recommended Citation
SARIKAHYA, N. B, & KIRMIZIGÜL, S (2012). Novel biologically active glycosides from the aerial parts of Cephalaria gazipashensis. Turkish Journal of Chemistry 36 (2): 323-334. https://doi.org/10.3906/kim-1105-32
