The synthesis of \alpha-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-\alpha-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
\alpha-Aminonitrile, Strecker synthesis, montmorillonite K10, dicationic phosphonium salt
YILDIRIM, ÇİĞDEM; YOLAÇAN, ÇİĞDEM; and AYDOĞAN, FERAY
"Synthesis of \alpha-aminonitriles catalyzed by montmorillonite K10 in the presence of dicationic phosphonium salt in water under ultrasonic effect,"
Turkish Journal of Chemistry: Vol. 36:
1, Article 8.
Available at: https://journals.tubitak.gov.tr/chem/vol36/iss1/8