Synthesis of \alpha-aminonitriles catalyzed by montmorillonite K10 in the presence of dicationic phosphonium salt in water under ultrasonic effect

Authors

ÇİĞDEM YILDIRIM
ÇİĞDEM YOLAÇAN
FERAY AYDOĞAN

DOI

10.3906/kim-1104-56

Abstract

The synthesis of \alpha-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-\alpha-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.

Keywords

\alpha-Aminonitrile, Strecker synthesis, montmorillonite K10, dicationic phosphonium salt

First Page

101

Last Page

109

Recommended Citation

YILDIRIM, ÇİĞDEM; YOLAÇAN, ÇİĞDEM; and AYDOĞAN, FERAY (2012) "Synthesis of \alpha-aminonitriles catalyzed by montmorillonite K10 in the presence of dicationic phosphonium salt in water under ultrasonic effect," Turkish Journal of Chemistry: Vol. 36: No. 1, Article 8. https://doi.org/10.3906/kim-1104-56
Available at: https://journals.tubitak.gov.tr/chem/vol36/iss1/8