Long chain dicationic ammonium salts (1a-1c), easily prepared from tert-amines and dihaloalkanes, were successfully used as efficient phase-transfer catalysts in the Michael addition reaction of various active methylene compounds to 2-cyclohexenone without solvent under ultrasonic irradiation. The investigated dicationic salts were more effective than monocationic tetrabutylammonium bromide, with short reaction times and high yields. This methodology was established under phase-transfer catalytic conditions and ultrasonic effects with many advantages, including the easy and cost-effective synthesis of the catalyst, mild reaction conditions, short reaction times, good yields, simple work-up procedures, and environmental friendliness.
ÖGE, AYTEK; MAVİŞ, MURAT EMRAH; YOLAÇAN, ÇİĞDEM; and AYDOĞAN, FERAY
"Solvent-free Michael addition of 2-cyclohexenone under ultrasonic irradiation in the presence of long chain dicationic ammonium salts,"
Turkish Journal of Chemistry: Vol. 36:
1, Article 11.
Available at: https://journals.tubitak.gov.tr/chem/vol36/iss1/11