Tridentate ligands derived from L-tert-Leucine for the Cu(II) mediated asymmetric Henry reaction

Authors

NESLİHAN KORKMAZ
DEMET ASTLEY
STEPHEN THOMAS ASTLEY

DOI

10.3906/kim-1009-15

Abstract

Chiral tridentate Schiff base ligands were prepared from L-tert-Leucine and used as catalysts in the asymmetric Henry reaction in the presence of Cu(II) ions. Moderate enantiomeric excesses (up to 66%) and yields (up to 76%) of the desired \beta-nitroalcohols were obtained.

Keywords

Asymmetric Henry reaction, chiral Schiff base, L-tert-Leucine, amino alcohol, tridentate ligand

First Page

361

Last Page

374

Recommended Citation

KORKMAZ, NESLİHAN; ASTLEY, DEMET; and ASTLEY, STEPHEN THOMAS (2011) "Tridentate ligands derived from L-tert-Leucine for the Cu(II) mediated asymmetric Henry reaction," Turkish Journal of Chemistry: Vol. 35: No. 3, Article 2. https://doi.org/10.3906/kim-1009-15
Available at: https://journals.tubitak.gov.tr/chem/vol35/iss3/2