Chemical composition and antimicrobial activity of the essential oils of Geranium columbinum L. and G. lucidum L. (Geraniaceae)

Authors

NIKO RADULOVIC
MILAN DEKIC
ZORICA STOJANOVIC-RADIC
RADOSAV PALIC

DOI

10.3906/kim-1002-43

Abstract

The chemistry of Geranium columbinum and G. lucidum volatiles has been studied here for the first time. The essential oils were obtained by hydrodistillation, analyzed by GC and GC-MS, and screened for their in vitro antibacterial and antifungal activity in a microdilution assay. In total, 172 constituents were identified, accounting for 88.1%-96.7% of the detected GC peak areas. The essential oils consisted mainly of fatty acids and fatty acid-derived compounds (65.0%-86.3%). The major compounds of the essential oils were hexadecanoic acid, hexahydrofarnesyl acetone, and tetracosane. The antimicrobial assay showed a strong activity of the oil from aerial parts of G. columbinum against the pathogenic yeast C. albicans (MIC = 0.437, MBC = 1.75 mg/mL).

Keywords

Geranium columbinum, Geranium lucidum, Geraniaceae, essential oil composition, hexadecanoic acid, hexahydrofarnesyl acetone, tetracosane, antimicrobial activity

First Page

499

Last Page

512

Recommended Citation

RADULOVIC, NIKO; DEKIC, MILAN; STOJANOVIC-RADIC, ZORICA; and PALIC, RADOSAV (2011) "Chemical composition and antimicrobial activity of the essential oils of Geranium columbinum L. and G. lucidum L. (Geraniaceae)," Turkish Journal of Chemistry: Vol. 35: No. 3, Article 13. https://doi.org/10.3906/kim-1002-43
Available at: https://journals.tubitak.gov.tr/chem/vol35/iss3/13