Synthesis and biological activity of 5-substituted-2-amino-1,3,4-oxadiazole derivatives

Authors

SANJEEV KUMAR

DOI

10.3906/kim-0908-177

Abstract

Electrical energy offers numerous benefits for performing synthesis, including increased reaction rates, enhanced yields, and cleaner chemistries. 5-Substituted-2-amino-1,3,4-oxadiazoles were synthesized directly from the semicarbazone at a platinum electrode under controlled potential electrolysis in an undivided cell assembly in acetonitrile. The compounds were screened for antibacterial and antifungal activity against Staphylococcus aureus, Klebsiella pneumoniae, Pellicularia salmonicolor, and Macrophomina phaseolina.

Keywords

Antibacterial, antifungal, controlled potential, electrolysis, platinum electrode

First Page

99

Last Page

108

Recommended Citation

KUMAR, SANJEEV (2011) "Synthesis and biological activity of 5-substituted-2-amino-1,3,4-oxadiazole derivatives," Turkish Journal of Chemistry: Vol. 35: No. 1, Article 9. https://doi.org/10.3906/kim-0908-177
Available at: https://journals.tubitak.gov.tr/chem/vol35/iss1/9