Ethyl 5-oxo-3-arylamino-2,5-dihydroisoxazole-4- carboxylates as sources of imidazopyrimidine and aminoindole derivatives

Authors

AHMAD POURSATTAR MARJANI
JABBAR KHALAFY

DOI

10.3906/kim-1002-73

Abstract

The reaction of ethyl 5-oxo-3-arylamino-2,5-dihydroisoxazole-4- carboxylates with 2-chloropyrimidine and 2-chlorobenzoxazole gave the corresponding isoxazolones with pyrimidine and benzoxazole rings substituted on N-2. Their rearrangements with triethylamine in ethanol produced the corresponding imidazopyrimidine and aminoindole derivatives, respectively, through intramolecular cyclisation.

Keywords

Isoxazolones, 2-chloropyrimidine, 2-chlorobenzoxazole, rearrangements, imidazopyrimidines, aminoindoles

First Page

847

Last Page

858

Recommended Citation

MARJANI, AHMAD POURSATTAR and KHALAFY, JABBAR (2010) "Ethyl 5-oxo-3-arylamino-2,5-dihydroisoxazole-4- carboxylates as sources of imidazopyrimidine and aminoindole derivatives," Turkish Journal of Chemistry: Vol. 34: No. 6, Article 2. https://doi.org/10.3906/kim-1002-73
Available at: https://journals.tubitak.gov.tr/chem/vol34/iss6/2