Sulfonic acid-functionalized silica: a remarkably efficient heterogeneous reusable catalyst for the one-pot synthesis of 1,4-dihydropyridines

Authors

BEHZAD MOHAMMADI
SAYYED MOHAMMAD HOSSEINI JAMKARANI
TAGHI A. KAMALI
MAHMOUD NASROLLAHZADEH
ALI MOHAJERI

Abstract

An efficient one-pot method for the synthesis of 1,4-dihydropyridines from \beta-dicarbonyl compounds, aldehyde, and ammonium acetate is reported using sulfonic acid-functionalized silica at 90 °C under solvent-free conditions with good to excellent yields. The catalyst is easily prepared, stable (up to 300 °C), reusable, and efficiently used under reaction conditions.

DOI

10.3906/kim-0906-28

Keywords

1, 4-Dihydropyridine, \beta-dicarbonyl compounds, solid acid, SiO_2-R-SO_3H, heterogeneous catalyst

First Page

613

Last Page

619

Recommended Citation

MOHAMMADI, B, JAMKARANI, S. M, KAMALI, T. A, NASROLLAHZADEH, M, & MOHAJERI, A (2010). Sulfonic acid-functionalized silica: a remarkably efficient heterogeneous reusable catalyst for the one-pot synthesis of 1,4-dihydropyridines. Turkish Journal of Chemistry 34 (4): 613-619. https://doi.org/10.3906/kim-0906-28