Molecular recognition of aromatic amines by coumarin substituted azacrown ether

Authors

HITEN MEHTA
HARJINDER KAUR
SHOBHANA MENON

DOI

10.3906/kim-0903-20

Abstract

New chromogenic azacrown ether N[7-hydroxy-4-methyl-coumarin-8-methylene]-4-azadibenzo-18-crownether (HMCMADCE) was synthesised through the condensation reaction of 4-azadibenzo-18-crown- 6ether, 4-methyl,7-hydroxy coumarin and formaldehyde was used to investigate its behaviour towards the aromatic amines. All the aromatic primary amines gave specific colours in aqueous medium. The functional group recognition behaviour is further extended to study the estimation of the aromatic primary amine in commercial drug samples. The amines can be estimated in the presence of several functional groups like phenolic-OH, secondary and tertiary aromatic amines as well as aliphatic amines.

Keywords

Chromogenic azacrown ether, primary aromatic amines, drug analysis, spectrophotometry.

First Page

417

Last Page

426

Recommended Citation

MEHTA, HITEN; KAUR, HARJINDER; and MENON, SHOBHANA (2010) "Molecular recognition of aromatic amines by coumarin substituted azacrown ether," Turkish Journal of Chemistry: Vol. 34: No. 3, Article 11. https://doi.org/10.3906/kim-0903-20
Available at: https://journals.tubitak.gov.tr/chem/vol34/iss3/11