Direct reductive amination of carbonyl compounds using sodium borohydride-silica chloride

Authors

HESHMATOLLAH ALINEZHAD
MAHMOOD TAJBAKHSH
NEDA HAMIDI

DOI

10.3906/kim-0903-46

Abstract

A simple and convenient procedure for reductive amination of aldehydes and ketones using sodium borohydride in the presence of silica chloride as an active, inexpensive, recoverable, and recyclable catalyst is described. The reactions were carried out with equimolar amounts of amine and carbonyl compound using silica chloride-sodium borohydride in THF at room temperature.

Keywords

Reductive amination, silica chloride, sodium borohydride, aldehyde, ketone.

First Page

307

Last Page

312

Recommended Citation

ALINEZHAD, HESHMATOLLAH; TAJBAKHSH, MAHMOOD; and HAMIDI, NEDA (2010) "Direct reductive amination of carbonyl compounds using sodium borohydride-silica chloride," Turkish Journal of Chemistry: Vol. 34: No. 2, Article 16. https://doi.org/10.3906/kim-0903-46
Available at: https://journals.tubitak.gov.tr/chem/vol34/iss2/16