Some bioactive organotin(IV) derivatives with 3,4-dichlorophenylacetic acid: synthesis, spectroscopic properties, and X-ray structure of [Sn_4(C_4H_9)_8(OOCCH_2C_6H_3Cl_2)_4O_2]

Authors

MUHAMMAD ADEEL SAEED
MUHAMMAD KHAWAR RAUF
. IMTIAZ-UD-DIN
AMIN BADSHAH
MUHAMMAD ZAEEM AKHTAR
BUSHRA MIRZA

DOI

10.3906/kim-0805-39

Abstract

Some bioactive organotin(IV) derivatives of 3,4-dichlorophenylacetic acid (HL) were synthesized by reacting the ligand acid with various di- or tri-organotin compounds (in suitable mole ratios) in the presence of triethylamine. The structural investigation was carried out via multinuclear (^1H, ^{13}C, and ^{119}Sn) NMR, IR spectroscopy, and X-ray crystallography. The crystal structure of 4 comprises a central Sn_2O_2 core with O atoms bonded to 2 dibutylbis(3,4-dichlorophenylacetato)tin(IV) units. All the Sn atoms of 4 are essentially 5-coordinated in distorted trigonal-bipyramidal geometry. Some of the compounds exhibited significant antibacterial and antifungal activity.

Keywords

Organotin(IV), spectroscopy, distannoxane, X-ray structure, antibacterial, antifungal.

First Page

109

Last Page

118

Recommended Citation

SAEED, MUHAMMAD ADEEL; RAUF, MUHAMMAD KHAWAR; IMTIAZ-UD-DIN, .; BADSHAH, AMIN; AKHTAR, MUHAMMAD ZAEEM; and MIRZA, BUSHRA (2010) "Some bioactive organotin(IV) derivatives with 3,4-dichlorophenylacetic acid: synthesis, spectroscopic properties, and X-ray structure of [Sn_4(C_4H_9)_8(OOCCH_2C_6H_3Cl_2)_4O_2]," Turkish Journal of Chemistry: Vol. 34: No. 1, Article 11. https://doi.org/10.3906/kim-0805-39
Available at: https://journals.tubitak.gov.tr/chem/vol34/iss1/11