A series of 8 new derivatives of fendiline was prepared for evaluation as allosteric modulators of GABA_B receptors: 4 based on acridine and 4 with restricted distance between the 2 aryl moieties.
Fendiline analogues, acridines, acridones, aminotetralins, aminoindanes, GABA.
KHALAFY, JABBAR; PRAGER, ROLF H.; and PUSPAWATI, NI MADE (2008) "Synthesis and Biological Activity of Allosteric Modulators of GABA_B Receptors. Part 4. Synthesis of Potentially Fluorescent Acridines and Conformationally Restricted N-(arylpropyl)-1-arylethylamines," Turkish Journal of Chemistry: Vol. 32: No. 6, Article 11. Available at: https://journals.tubitak.gov.tr/chem/vol32/iss6/11