4(5)-Chloro-imidazole-5(4)-carboxaldehyde derivatives are important precursors for the preparation of biologically active compounds. We developed a simple, novel, and efficient method for the synthesis of these compounds. The chemistry described is amenable to large-scale use and is flexible enough to allow the preparation of analogs.
DAVOOD, ASGHAR; ALIPOUR, ESKANDAR; and SHAFIEE, ABBAS (2008) "Efficient Synthesis of Imidazole Derivatives: An Important Synthon for the Preparation of Biologically Active Compounds," Turkish Journal of Chemistry: Vol. 32: No. 3, Article 11. Available at: https://journals.tubitak.gov.tr/chem/vol32/iss3/11