A New Ursane-type Triterpenoid from Salvia santolinifolia

Authors

ZAHER AHMAD
SAJID MEHMOOD
REHANA IFZAL
ABDUL MALIK
NIGHAT AFZA
MOHAMMAD ASHRAF
ERUM JAHAN

DOI

-

Abstract

Santolinoic acid (1), a new ursane-type triterpene was isolated from the chloroform soluble fraction of Salvia santolinifolia. Its structure was established as 2\alpha, 3\beta, 9\alpha-trihydroxyurs-12-en-28-oic acid on the basis of spectroscopic analysis, including high resolution mass spectroscopy, and 1- and 2-dimensional NMR techniques. The compound (1) showed inhibitory activity against the enzymes acetylcholinesterase and butyrylcholinesterase.

Keywords

Salvia santolinifolia, Labiatae, triterpenoid, enzyme inhibition

First Page

495

Last Page

501

Recommended Citation

AHMAD, ZAHER; MEHMOOD, SAJID; IFZAL, REHANA; MALIK, ABDUL; AFZA, NIGHAT; ASHRAF, MOHAMMAD; and JAHAN, ERUM (2007) "A New Ursane-type Triterpenoid from Salvia santolinifolia," Turkish Journal of Chemistry: Vol. 31: No. 4, Article 13. Available at: https://journals.tubitak.gov.tr/chem/vol31/iss4/13