Turkish Journal of Chemistry
DOI
-
Abstract
A chemoenzymatic synthesis of 2-bromo-6-hydroxy-3-methoxy-2- cyclohexen-1-one starting from cyclohexane-1,3-dione is reported. Manganese(III) acetate-mediated acetoxylation followed by the enzyme-mediated hydrolysis of \alpha'-acetoxy enone affords hydroxy-enone 5 and acetoxy enone 4 with high enantiomeric excesses in good yields.
Keywords
Chemoenzymatic synthesis, cyclic polyoxo cyclohexenones, manganese(III) acetate, acetoxylation
First Page
149
Last Page
153
Recommended Citation
KARAASLAN, EMİNE ÖZGÜL and TOKA, YASEMİN (2007) "Chemoenzymatic Synthesis of 2-Bromo-6-Hydroxy-3-Methoxy-2-Cyclohexen-1-one," Turkish Journal of Chemistry: Vol. 31: No. 2, Article 5. Available at: https://journals.tubitak.gov.tr/chem/vol31/iss2/5
