Basic alumina is employed as an inorganic basic solid catalyst for the clean and less hazardous protection of carbonyl compounds, such as phenylhydrazones, 2,4-dinitrophenylhydrazones, semicarbazones, and thiosemicarbazones, under solvent-free conditions. The reactions proceed smoothly and require a short reaction time with good to excellent yields, and the alumina used can be recycled.
Basic alumina, phenylhydrazine derivatives, semicarbazides, carbonyl compounds, protection, recyclable
NIKNAM, KHODABAKHSH; KIASAT, ALI REZA; KARAMI, BAHADOR; and HEYDARI, NIMA (2007) "Basic Al_2O_3 as a Recyclable Reagent for the Protection of Carbonyl Groups with Phenylhydrazine Derivatives and Semicarbazides," Turkish Journal of Chemistry: Vol. 31: No. 2, Article 3. Available at: https://journals.tubitak.gov.tr/chem/vol31/iss2/3