Synthesis and Antimicrobial Activity of Some New 3-Substituted Benzyl-5-(4-chloro-2-piperidin-1yl-thiazole-5-yl-methylene)-thiazolidine-2,4-dione Derivatives

Authors

MELTEM CEYLAN ÜNLÜSOY
OYA BOZDAĞ DÜNDAR
NURTEN ALTANLAR
RAHMİYE ERTAN

DOI

-

Abstract

A new series of thiazolyl thiazolidine-2,4-dione (Va-f) were synthesized and their structures were elucidated by IR, ^1H-NMR, mass spectra and elementary analysis. The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus subtilis and Escherichia coli. Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin.

Keywords

Thiazolidine-2, 4-diones, thiazole derivatives, antimicrobial activities

First Page

355

Last Page

360

Recommended Citation

ÜNLÜSOY, MELTEM CEYLAN; DÜNDAR, OYA BOZDAĞ; ALTANLAR, NURTEN; and ERTAN, RAHMİYE (2006) "Synthesis and Antimicrobial Activity of Some New 3-Substituted Benzyl-5-(4-chloro-2-piperidin-1yl-thiazole-5-yl-methylene)-thiazolidine-2,4-dione Derivatives," Turkish Journal of Chemistry: Vol. 30: No. 3, Article 10. Available at: https://journals.tubitak.gov.tr/chem/vol30/iss3/10