Turkish Journal of Chemistry
Studies on 2-Ethyl-3-carbmethoxy-4-aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline Derivatives and Calcium Modulatory Activities
Twelve new compounds having a 2-ethyl-3-carbmethoxy-4-aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline structure were synthesized, characterized and screened for their calcium modulatory activities. The calcium antagonistic activities of the compounds were investigated by tests performed on isolated rat ileum and lamb carotid artery. Compounds 1, 4, 8 and 9 showed considerable activity.
Dihydropyridine, hexahydroquinoline, antihypertensive activity, calcium antagonist
ŞAFAK, CİHAT; DOĞAN, ELVAN; and EROL, KEVSER (2006) "Studies on 2-Ethyl-3-carbmethoxy-4-aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline Derivatives and Calcium Modulatory Activities," Turkish Journal of Chemistry: Vol. 30: No. 1, Article 13. Available at: https://journals.tubitak.gov.tr/chem/vol30/iss1/13