Turkish Journal of Chemistry
DOI
-
Abstract
Twelve new compounds having a 2-ethyl-3-carbmethoxy-4-aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline structure were synthesized, characterized and screened for their calcium modulatory activities. The calcium antagonistic activities of the compounds were investigated by tests performed on isolated rat ileum and lamb carotid artery. Compounds 1, 4, 8 and 9 showed considerable activity.
Keywords
Dihydropyridine, hexahydroquinoline, antihypertensive activity, calcium antagonist
First Page
109
Last Page
117
Recommended Citation
ŞAFAK, CİHAT; DOĞAN, ELVAN; and EROL, KEVSER (2006) "Studies on 2-Ethyl-3-carbmethoxy-4-aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline Derivatives and Calcium Modulatory Activities," Turkish Journal of Chemistry: Vol. 30: No. 1, Article 13. Available at: https://journals.tubitak.gov.tr/chem/vol30/iss1/13
