Turkish Journal of Chemistry
Abstract
Five Pt(II) complexes with the ligands 2-ethyl-/ or-benzyl-/ or-phenoxymethyl- and 1-methyl-2-hydroxymethyl- and 1-methyl-2-phenyl- benzimidazoles were synthesized and characterized by elemental analysis, and IR and ^1H-NMR spectra and evaluated for their in vitro genotoxic activities by Rec-Assay test. Based on the data obtained in this study, the Pt(II) complexes tested might be taken into consideration as promising antitumor compounds.
DOI
-
Keywords
Benzimidazol, Platinum(II) complexes, In vitro genotoxic activity, Rec-Assay test
First Page
607
Last Page
615
Recommended Citation
ALGÜL, Ö, ÖZÇELİK, B, ABBASOĞLU, U, & GÜMÜŞ, F (2005). Synthesis, Characterization and Genotoxicity of Platinum(II)Complexes With Subtituted Benzimidazole Ligands. Turkish Journal of Chemistry 29 (6): 607-615. https://doi.org/-
