Turkish Journal of Chemistry
Abstract
Five Pt(II) complexes with the ligands 2-ethyl-/ or-benzyl-/ or-phenoxymethyl- and 1-methyl-2-hydroxymethyl- and 1-methyl-2-phenyl- benzimidazoles were synthesized and characterized by elemental analysis, and IR and ^1H-NMR spectra and evaluated for their in vitro genotoxic activities by Rec-Assay test. Based on the data obtained in this study, the Pt(II) complexes tested might be taken into consideration as promising antitumor compounds.
DOI
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Keywords
Benzimidazol, Platinum(II) complexes, In vitro genotoxic activity, Rec-Assay test
First Page
607
Last Page
615
Recommended Citation
ALGÜL, ÖZTEKİN; ÖZÇELİK, BERRİN; ABBASOĞLU, UFUK; and GÜMÜŞ, FATMA (2005) "Synthesis, Characterization and Genotoxicity of Platinum(II)Complexes With Subtituted Benzimidazole Ligands," Turkish Journal of Chemistry: Vol. 29: No. 6, Article 4. Available at: https://journals.tubitak.gov.tr/chem/vol29/iss6/4
