Three known triterpene glycosides were isolated from the MeOH extract of dried and powdered seeds of Nigella sativa. The structures of the compounds were established as 3-O-[\beta-D-xylopyranosyl- (1 \to 3)-\alpha-L-rhamnopyranosyl-(1 \to 2)-\alpha -L-arabinopyranosyl]- 28-O-[\alpha-L-rhamnopyranosyl-(1 \to 4)-\beta-D-glucopyranosyl-(1 \to 6)- \beta-D-glucopyranosyl]-hederagenin (1), 3-O-[\alpha -L-rhamnopyranosyl- (1 \to 2)-\alpha-L-arabinopyranosyl]-28-O-[\alpha -L-rhamnopyranosyl-(1 \to 4)- \beta-D-glucopyranosyl-(1\to 6)-\beta-D-glucopyranosyl]-hederagenin (2), and 3-O-[\beta-D-xylopyranosyl- (1\to 3)-\alpha-L-rhamnopyranosyl-(1\to 2)-\alpha- L-arabinopyranosyl]-hederagenin (3) by means of chemical and spectral methods. Compound 2 was isolated for the first time from the genus Nigella.
Ranunculaceae, Nigella sativa, Saponins, Triterpene glycoside, hederagenin
TAŞKIN, MUSTAFA KEMAL; ÇALIŞKAN, ÖZGEN ALANKUŞ; ANIL, HÜSEYİN; ABOU-GAZAR, HASSAN; KHAN, IKHLAS A.; and BEDİR, ERDAL (2005) "Triterpene Saponins from Nigella sativa L.," Turkish Journal of Chemistry: Vol. 29: No. 5, Article 14. Available at: https://journals.tubitak.gov.tr/chem/vol29/iss5/14