Turkish Journal of Chemistry
DOI
-
Abstract
To gain more information about the effect of solvent on \alpha -amino acid benzyl- and t-butyl- esters, the stoichiometric protonation constants of 10 esters (glycine benzyl ester, L-alanine benzyl ester, L-valine benzyl ester, L-serine benzyl ester, glycine t-butyl ester, L-alanine t-butyl ester, L-valine t-butyl ester, L-leucine t-butyl ester, L-phenylalanine t-butyl ester and L-isoleucine t-butyl ester) in 20%-80% (v/v) ethanol-water mixtures were determined at an ionic strength of 0.10 M NaCl and at 25.0 \pm 0.1 °C under nitrogen atmosphere. A potentiometric method was used and the calculation of constants was carried out using the PKAS computer program. The logarithm of the protonation constants of the above-mentioned \alpha -amino acid esters linearly decreased with increases in ethanol contents but the values that determined 80% ethanol did not follow this linear trend. The variation of these constants is discussed on the basis of specific solute-solvent interactions.
Keywords
Potentiometry; protonation constants, solvent effect, amino acid esters
First Page
41
Last Page
48
Recommended Citation
DOĞAN, ALEV and KILIÇ, ESMA (2005) "Potentiometric Studies on the Protonation Constants and Solvation of Some \alpha-Amino Acid Benzyl- and t-Butyl- Esters in Ethanol-Water Mixtures," Turkish Journal of Chemistry: Vol. 29: No. 1, Article 5. Available at: https://journals.tubitak.gov.tr/chem/vol29/iss1/5
