Studies on the Reactions of 4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3- furandione with Some NH Nucleophiles

Authors

AHMET ŞENER
HASAN GENÇ
İSRAFİL TOZLU
M. KASIM ŞENER

Abstract

4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3-furandione 1 was reacted with o-phenylenediamine, substituted ureas and methylcarbamate or acetamide to give quinoxaline 2, pyrimidine 3 and benzoylmalonic acid 4 derivatives, respectively. Benzoylmalonic acid derivative 4a was converted into a new oxozinedione derivative, 5, by refluxing its solution in xylene containing a catalytic amount of p-toluene sulfonic acid. In addition, triphenylpyrazole carboxylic acid derivative 6 was obtained from the reaction of 4a with diphenylhydrazine.

DOI

-

Keywords

Cyclic oxalyl compounds, quinoxaline, pyrimidine, benzoylmalonic acid, oxazine, pyrazole carboxylic acid.

First Page

659

Last Page

666

Recommended Citation

ŞENER, A, GENÇ, H, TOZLU, İ, & ŞENER, M. K (2004). Studies on the Reactions of 4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3- furandione with Some NH Nucleophiles. Turkish Journal of Chemistry 28 (5): 659-666. https://doi.org/-