Onosma argentatum Hub.-Mor. is an endemic species growing in Turkey. In this study, the roots of O. argentatum were extracted with n-hexane-dichloromethane (1:1). The extract was separated on a silica gel column eluting with n-hexane-ethyl acetate by gradient elution. New naphthoquinone compounds (3 known and 1 new) were isolated and their structures were elucidated by spectroscopic methods as deoxyshikonin, acetyl shikonin, 3-hydroxy-isovaleryl shikonin, and 5,8-O-dimethyl acetyl shikonin.
Onosma argentatum, natural naphthoquinones, shikonin derivatives, Boraginaceae, 5, 8-O-dimethyl acetyl shikonin
ÖZGEN, UFUK; COŞKUN, MAKSUT; KAZAZ, CAVİT; and SEÇEN, HASAN (2004) "Naphthoquinones from the Roots of Onosma argentatum Hub.-Mor. (Boraginaceae)," Turkish Journal of Chemistry: Vol. 28: No. 4, Article 6. Available at: https://journals.tubitak.gov.tr/chem/vol28/iss4/6