Iridoid and Phenylethanoid Glycosides from Verbascum lasianthum

Authors

ZELİHA Ş. AKDEMİR
İ. İREM TATLI
ERDAL BEDİR
IKHLAS A. KHAN

DOI

-

Abstract

Three iridoid glucosides, 8-O-acethylharpagide (1), harpagoside (2), and 6-O-vanilloylajugol (3), were isolated from the roots of Verbascum lasianthum Boiss. ex Bentham. In addition, 2 phenylethanoid glycosides, verbascoside {=acteoside, [\beta -(3,4-dihydroxyphenyl)-ethyl]-(3' -O-\alpha -L-rhamnopyranosyl)-(4' -O-caffeoyl)-\beta -D-glucopyranoside} (4) and poliumoside {= [\beta -(3,4-dihydroxyphenyl)-ethyl]-(3',6' -O-\alpha -L-dirhamnopyranosyl)-(4' -O-caffeoyl)-\beta -D-glucopyranoside} (5), were also isolated. The structures of all compounds were established by spectroscopic evidence (UV, IR, 1D and 2D NMR, LC-ESIMS). Compounds 2-5 demonstrated scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical in TLC autographic assays.

Keywords

Verbascum lasianthum, Scrophulariaceae, iridoid glucosides, 8-O-acethylharpagide, harpagoside, 6-O-vanilloylajugol, phenylethanoid glycosides, verbascoside (= acteoside), poliumoside, radical scavenging activity

First Page

227

Last Page

234

Recommended Citation

AKDEMİR, ZELİHA Ş.; TATLI, İ. İREM; BEDİR, ERDAL; and KHAN, IKHLAS A. (2004) "Iridoid and Phenylethanoid Glycosides from Verbascum lasianthum," Turkish Journal of Chemistry: Vol. 28: No. 2, Article 11. Available at: https://journals.tubitak.gov.tr/chem/vol28/iss2/11