Quantitative Analysis of l-Hyoscyamine in Hyoscyamus reticulatus L. by GC-MS

Authors

MURAT KARTAL
SEMRA KURUCU
LEVENT ALTUN
TİMURHAN CEYHAN
ESİN SAYAR
ŞEMSETTİN CEVHEROĞLU
YALCIN YETKİN

DOI

-

Abstract

The hyoscyamine content of leaves and root samples of Hyoscyamus reticulatus} L. from Bulanık, Muş in east Anatolia, Turkey, was determined by capillary GC-MS to be 0.036 \pm 0.004% in the leaves and 0.056 \pm 0.011\% in the roots as the predominant compound. Sopolamine was only detected in trace amounts. These findings are in accordance with reports on hyoscyamine content in Hyoscyamus} species. The limit of detection was 3.125 \mu g/mL and the limit of quantification was 6.25 \mu g/mL for hyoscyamine. This method has been shown to be linear and sensitive.

Keywords

l-Hyoscyamine, Hyoscyamus reticulatus L., Capillary GC-MS

First Page

565

Last Page

570

Recommended Citation

KARTAL, MURAT; KURUCU, SEMRA; ALTUN, LEVENT; CEYHAN, TİMURHAN; SAYAR, ESİN; CEVHEROĞLU, ŞEMSETTİN; and YETKİN, YALCIN (2003) "Quantitative Analysis of l-Hyoscyamine in Hyoscyamus reticulatus L. by GC-MS," Turkish Journal of Chemistry: Vol. 27: No. 5, Article 4. Available at: https://journals.tubitak.gov.tr/chem/vol27/iss5/4