Quantitative Analysis of l-Hyoscyamine in Hyoscyamus reticulatus L. by GC-MS

Authors

MURAT KARTAL
SEMRA KURUCU
LEVENT ALTUN
TİMURHAN CEYHAN
ESİN SAYAR
ŞEMSETTİN CEVHEROĞLU
YALCIN YETKİN

Abstract

The hyoscyamine content of leaves and root samples of Hyoscyamus reticulatus} L. from Bulanık, Muş in east Anatolia, Turkey, was determined by capillary GC-MS to be 0.036 \pm 0.004% in the leaves and 0.056 \pm 0.011\% in the roots as the predominant compound. Sopolamine was only detected in trace amounts. These findings are in accordance with reports on hyoscyamine content in Hyoscyamus} species. The limit of detection was 3.125 \mu g/mL and the limit of quantification was 6.25 \mu g/mL for hyoscyamine. This method has been shown to be linear and sensitive.

DOI

-

Keywords

l-Hyoscyamine, Hyoscyamus reticulatus L., Capillary GC-MS

First Page

565

Last Page

570

Recommended Citation

KARTAL, M, KURUCU, S, ALTUN, L, CEYHAN, T, SAYAR, E, CEVHEROĞLU, Ş, & YETKİN, Y (2003). Quantitative Analysis of l-Hyoscyamine in Hyoscyamus reticulatus L. by GC-MS. Turkish Journal of Chemistry 27 (5): 565-570. https://doi.org/-