Turkish Journal of Chemistry
Abstract
4-Fenoldiazonium tetrafluoroborate and 4-benzoicaciddiazonium tetrafluoroborate was prepared and was shown to be an effective DNA cleavage agent in the presence of the 1-electron donor copper(II) chloride. Its mechanism involves the generation of the aryl radical cleaving DNA by hydrogen atom abstraction from deoxyribose sugar.
DOI
-
Keywords
Aryl radicals, diazonium salts, DNA cleavage
First Page
539
Last Page
544
Recommended Citation
KIZIL, M, YILMAZ, E. İ, PİRİNÇÇİOĞLU, N, & AYTEKİN, Ç (2003). DNA Cleavage Activity of Diazonium Salts: Chemical Nucleases. Turkish Journal of Chemistry 27 (5): 539-544. https://doi.org/-