Turkish Journal of Chemistry
Alnustone, 4(E),6(E)-1,7-diphenyl-hepta-4,6-dien-3-one, was synthesized starting from benzaldehyde in three steps with an overall yield of 57%. The condensation of benzaldehyde with acetone gave benzalacetone. The Pd-C catalyzed hydrogenation of benzalacetone afforded benzylacetone. The in situ enamination of benzylacetone with pyrrolidine and acetic acid followed by cinnamaldehyde treatment gave alnustone.
alnustone, 4(E), 6(E)-1, 7-diphenyl-hepta-4, 6-dien-3-one, diarylheptanoid, benzaldehyde, benzalacetone, benzylacetone, cinnamaldehyde
GÖKSU, SÜLEYMAN; ÇELİK, HÜLYA; and SEÇEN, HASAN (2003) "An Efficient Synthesis of Alnustone, a Naturally Occurring Compound," Turkish Journal of Chemistry: Vol. 27: No. 1, Article 5. Available at: https://journals.tubitak.gov.tr/chem/vol27/iss1/5