Abstract

Alnustone, 4(E),6(E)-1,7-diphenyl-hepta-4,6-dien-3-one, was synthesized starting from benzaldehyde in three steps with an overall yield of 57%. The condensation of benzaldehyde with acetone gave benzalacetone. The Pd-C catalyzed hydrogenation of benzalacetone afforded benzylacetone. The in situ enamination of benzylacetone with pyrrolidine and acetic acid followed by cinnamaldehyde treatment gave alnustone.

DOI

Keywords

alnustone, 4(E), 6(E)-1, 7-diphenyl-hepta-4, 6-dien-3-one, diarylheptanoid, benzaldehyde, benzalacetone, benzylacetone, cinnamaldehyde

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Recommended Citation

GÖKSU, S, ÇELİK, H, & SEÇEN, H (2003). An Efficient Synthesis of Alnustone, a Naturally Occurring Compound. Turkish Journal of Chemistry 27 (1): 31-34. https://doi.org/-

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