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Turkish Journal of Chemistry

DOI

-

Abstract

A new spectrophotometric method based on the formation of an ion-pair using bromothymol blue as ion-pair complexing reagent was developed for the determination of mexiletine hydrochloride in capsules. The ion-pair formed was highly coloured and easily extracted with dichloromethane. The calibration curve was linear over the concentration range 1.08--10.8 \mu g.ml^{-1} at \lambda_{max} = 408 nm (r = 0.9999). The results obtained from the developed method were compared statistically with those obtained by the British Pharmacopeia method.

First Page

839

Last Page

842

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