Turkish Journal of Chemistry
Abstract
A very simple spectrophotometric method using measurements at zero-crossing wavelength is described for resolving binary mixtures of the food dyes, Sunset Yellow (E-110) and Quinoline Yellow (E-104). Calibration graphs are linear up to 15.0 \mu gml^{-1} of Sunset Yellow (r = 0.9998), and Quinoline Yellow (r = 0.9999). The assay procedure for E-110 and E-104 in pharmaceutical products involves the extraction of the dyes with AcOH/NaOAc buffer solution (pH = 4.5), filtration, and measurement of the second derivative absorbance values at 410.0 nm for E-104 and 533.1 nm for E-110. This method was used for determining synthetic mixtures of these dyes in different ratios and it was successfully applied to two commercial products without a previous separation step.
DOI
-
Keywords
Dyes, derivative spectrophotometry, pharmaceutical products, Sunset Yellow, Quinoline Yellow
First Page
501
Last Page
508
Recommended Citation
ÖZGÜR, M. Ü, & KOYUNCU, İ (2002). The Simultaneous Determination of Quinoline Yellow (E-104) and Sunset Yellow (E-110) in Syrups and Tablets by Second Derivative Spectrophotometry. Turkish Journal of Chemistry 26 (4): 501-508. https://doi.org/-
