Turkish Journal of Chemistry
Two Sideritis species afforded eleven kaurene and one beyerene diterpenes. Structures of the compounds from Sideritis sipylea} were elucidated as linearol (1), 7-epicandicandiol (2), sideridiol (3), siderol (4), isolinearol (5), isosidol (6) and epoxyisolinearol (7). Linearol was treated with m -chloroperbenzoic to afford its analogues ent-3\beta ,7\alpha ,17-trihydroxy-18-acetoxykaur-15-ene (1a) and ent}-7\alpha ,17,18-trihydroxy-3\beta -acetoxykaur-15-ene (1b) as new compounds. From the second species, Sideritis dichotoma, the kaurenes sideridiol (3) siderol (4), ent-7\alpha ,18-dihydroxy-15\beta ,16\beta -epoxykaurane (8)}, ent}-7\alpha -acetoxy,18-hydroxy-15\beta ,16\beta -epoxykaurane (9), ent-7\alpha -acetoxy-15,18-dihydroxy-kaur-16-ene (10), ent-7\alpha ,15,18-trihydroxykaur-16-ene (11) and the beyerene ent-7\alpha ,18-dihydroxybeyer-15-ene (12) were isolated. Structural elucidation is based on NMR techniques and mass spectrometer analyses.
Labiatae, Sideritis sipylea, Sideritis dichotoma, diterpenoids, kaurane, kaurene, beyerene.
TOPÇU, GÜLAÇTI; GÖREN, AHMET C.; KILIÇ, TURGUT; YILDIZ, Y. KEMAL; and TÜMEN, GÜLENDAM (2002) "Diterpenes from Sideritis sipylea and S. dichotoma," Turkish Journal of Chemistry: Vol. 26: No. 2, Article 6. Available at: https://journals.tubitak.gov.tr/chem/vol26/iss2/6