Towards the Asymmetric Synthesis of Ascochlorin

Authors

ÖZDEMİR DOĞAN
WOLFGANG OPPOLZER

DOI

-

Abstract

A synthetic approach is described to the asymmetric synthesis of ascochlorin (1), an antiviral antibiotic, based on the construction of a sesquiterpene unit via asymmetric Diels-Alder reaction of tigloyl sultam 4 & butadiene, and the introduction of the aromatic side chain (C9-C12 unit) by employing cuprate chemistry.

First Page

273

Last Page

281

Recommended Citation

DOĞAN, ÖZDEMİR and OPPOLZER, WOLFGANG (2001) "Towards the Asymmetric Synthesis of Ascochlorin," Turkish Journal of Chemistry: Vol. 25: No. 3, Article 4. Available at: https://journals.tubitak.gov.tr/chem/vol25/iss3/4