Transition Metal Compound Mediated Reduction of \alpha-Amino Acids to 1,2-Amino Alcohols with NaBH_4 in Water

Authors

AYHAN S. DEMİR
İDRIS M. AKHMEDOV
ÖZGE ŞEŞENOĞLU

Abstract

A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH_4 in the presence of NiCl_2 or MoO_3 in water give 1,2-amino alcohols in high yield. When optically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.

DOI

-

First Page

123

Last Page

126

Recommended Citation

DEMİR, A. S, AKHMEDOV, İ. M, & ŞEŞENOĞLU, Ö (1999). Transition Metal Compound Mediated Reduction of \alpha-Amino Acids to 1,2-Amino Alcohols with NaBH_4 in Water. Turkish Journal of Chemistry 23 (2): 123-126. https://doi.org/-