Turkish Journal of Chemistry
Abstract
This study describes the optimal conditions for the determination of Thioridazine HCl (Tz-HCl) in 0.2 M sulphuric acid by voltammetry using ruthenium (Ru), platinum (Pt) and glassy carbon (GC) electrodes. A new and sensitive method is described for electrochemical determination of Tz-HCl in the concentration range $5.10^{-5} - 10^{-3}$ M (20.35-407 $\mu$gml$^{-1}$); $6.10^{-4} - 10^{-2}$ M (244.2 - 4070 $\mu$gml$^{-1}$); $10^{-4} - 10^{-3}$ M (40,7 - 407 $\mu$gml$^{-1}$), with Ru, Pt and glassy carbon electrodes, respectively. The method was applied successfully to the determination of Tz-HCl in pure form or incorporated in their representative pharmaceutical preparations. The precision of the assay was comparable with that of the official assays.
DOI
-
Keywords
Thioridazine hydrochloride; voltammetry; ruthenium, platinum, glassy carbon electrodes.
First Page
325
Last Page
334
Recommended Citation
BİRYOL, İ, & DERMİŞ, S (1998). Voltammetric Determination of Thioridazine Hydrochloride. Turkish Journal of Chemistry 22 (4): 325-334. https://doi.org/-
