Turkish Journal of Biology
Author ORCID Identifier
DİLEK DEMİRCAN ÇEKER: 0009-0005-2913-4410
VOLKAN BAYSUNGUR: 0000-0003-1053-1051
SERDAR EVMAN: 0000-0002-1672-966X
İLKER KOLBAŞ: 0000-0003-1656-9595
ABDURRAHİM GÖRDEBİL: 0000-0002-4915-0830
SİNEM NALBANTOĞLU: 0000-0002-7067-6220
YUSUF TAMBAĞ: 0009-0005-6404-8630
ÖMER KAÇAR: 0000-0002-5402-2809
AHMET MİDİ: 0000-0002-6197-7654
HATİCE ASLANOĞLU: 0000-0002-1772-625X
NÜLÜFER KARA: 0009-0005-3809-1096
NİLGÜN ALGAN: 0009-0001-0026-4925
AYBERK BOYACIOĞLU: 0000-0002-1513-201X
BETÜL KARADEMİR YILMAZ: 0000-0003-1762-0284
ALİ ŞAHİN: 0000-0001-5594-1551
HİVDA ÜLBEĞİ POLAT: 0000-0001-8424-6849
ABİDİN ŞEHİTOĞULLARI: 0000-0002-4897-4205
ALİ ÇIBIKDİKEN: 0000-0003-4553-8202
MÜCAHİT BÜYÜKYILMAZ: 0009-0002-0117-2886
İBRAHİM AYDİLEK: 0000-0001-8037-8625
ABDULKERİM ENEŞ: 0009-0004-2637-4227
SEVDE KÜÇÜKER: 0009-0002-4162-439X
FATİH KARAKAYA: 0000-0003-2667-3724
İHSAN BOYACI: 0000-0001-7369-0426
MAHMUT GÜMÜŞ: 0000-0003-1899-0455
ONUR ŞENOL: 0000-0002-0252-396X
MERVE ÖZTUĞ: 0000-0002-6287-2774
EVREN SABAN: 0000-0002-1968-1470
ÖMER SOYSAL: 0000-0002-8832-9171
NUR BÜYÜKPINARBAŞILI: 0000-0002-1784-6665
AKİF TURNA: 0000-0003-3229-830X
MEHMET GÜNLÜOĞLU: 0000-0002-6952-3470
ASLI ÇAKIR: 0000-0003-0128-6947
ŞABAN TEKİN: 0000-0003-2641-6293
UYGAR TAZEBAY: 0000-0003-1999-8213
ABDULLAH KARADAĞ: 0000-0003-0969-7038
DOI
10.55730/1300-0152.2696
Abstract
Background/aim: LUNGBANK was established as a pioneering biorepository dedicated to lung cancer. Designed for streamlined biospecimens handling, it employs high-volume technologies to secure high-quality samples. Fortified with robust data management, LUNGBANK efficiently integrates diverse datasets. This strategic infrastructure positions LUNGBANK as more than a biospecimens repository; it operates as a sophisticated platform for advanced lung cancer research, amplifying the potential for meaningful discoveries.Materials and methods: LUNGBANK is intricately designed to streamline the collection, transfer, storage, and processing of biospecimens, employing high-volume technologies to ensure the acquisition of high-quality biological specimens. The system is fortified with robust data management protocols, facilitating efficient integration of diverse datasets. This strategic infrastructure ensures that LUNGBANK not only serves as a repository of biospecimens but also operates as a sophisticated platform for advanced lung cancer research.Results: LUNGBANK plays an essential role in furnishing a rich collection of biospecimens essential for unraveling the molecules and mechanisms linked to lung cancer. Rigorous standard operating procedures guided the meticulous collection of biospecimens, subjecting them to stringent quality control measures before inclusion in the study. Moreover, LUNGBANK has proven valuable in the establishment of patient-derived systems. The incorporation of cutting-edge technologies guarantees the acquisition of top-tier data, thereby amplifying the likelihood of substantial breakthroughs in both contemporary translational research and traditional histological evaluations.Conclusion: The establishment of LUNGBANK marks a significant stride towards addressing the pressing need for effective diagnostic and therapeutic systems in lung cancer research. By facilitating the collection and analysis of high-quality biospecimens, LUNGBANK serves as a valuable resource for unraveling the molecular intricacies of lung cancer initiation and progression. This comprehensive system not only supports Project LUNGMARK but also contributes to the broader landscape of personalized medicine, tailoring interventions to the specific needs of lung cancer patients.
Keywords
Biobank, Biorepository, integrative multiomics, Lung cancer, P-medicine
First Page
203
Last Page
217
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
DEMİRCAN ÇEKER, DİLEK; BAYSUNGUR, VOLKAN; EVMAN, SERDAR; KOLBAŞ, İLKER; GÖRDEBİL, ABDURRAHİM; NALBANTOĞLU, SİNEM M.; TAMBAĞ, YUSUF; KAÇAR, ÖMER; MİDİ, AHMET; ASLANOĞLU, HATİCE; KARA, NÜLÜFER; ALGAN, NİLGÜN; BOYACIOĞLU, AYBERK; KARADEMİR YILMAZ, BETÜL; ŞAHİN, ALİ; ÜLBEĞİ POLAT, HİVDA; ŞEHİTOĞULLARI, ABİDİN; ÇIBIKDİKEN, ALİ OSMAN; BÜYÜKYILMAZ, MÜCAHİT; AYDİLEK, İBRAHİM BERKAN; ENEŞ, ABDULKERİM; KÜÇÜKER, SEVDE; KARAKAYA, FATİH; BOYACI, İHSAN; GÜMÜŞ, MAHMUT; ŞENOL, ONUR; ÖZTUĞ, MERVE; SABAN, EVREN; SOYSAL, ÖMER; BÜYÜKPINARBAŞILI, NUR; TURNA, Akif; GÜNLÜOĞLU, Mehmet Zeki; ÇAKIR, Aslı; TEKİN, Şaban; TAZEBAY, Uygar; and KARADAĞ, Abdullah
(2024)
"LUNGBANK: A Novel Biorepository Strategy Tailored for Comprehensive Multi-Omics Analysis and P-Medicine Applications in Lung Cancer,"
Turkish Journal of Biology: Vol. 48:
No.
3, Article 6.
https://doi.org/10.55730/1300-0152.2696
Available at:
https://journals.tubitak.gov.tr/biology/vol48/iss3/6